Sep 2026
A rare germline TXNIP missense mutation may contribute to the genesis of Familial ovarian mature teratoma in human.
Findings establish TXNIP as the first functional candidate susceptibility gene for this phenotype and connect inherited susceptibility to ubiquitin-dependent protein turnover, GLUT1-driven metabolic reprogramming, and PI3K/mTOR-dominant follicular signaling.
Ya-Nan Zhang, Yan Li, Ya-Kun Liu et al.
· Molecular and Cellular Endoc... · 0 citations