Gestational exposure to per- and polyfluoroalkyl substances drives maternal liver dysfunction through lipid dysregulation and NF-κB/EGFR-STAT3 inflammatory activation.
Per- and polyfluoroalkyl substances (PFAS) are ubiquitous persistent pollutants in pregnant women, yet mechanisms of PFAS-triggered gestational liver injury remain poorly understood. This work quantified 18 serum PFAS in 221 pregnant participants and explored PFAS-liver function associations via epidemiological analyse...