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Open access Sep 2026

Higher cystatin C, but not creatinine, predicts frailty risk in individuals with normal kidney function

Objective This study investigates the associations of creatinine and cystatin C with frailty risk in individuals with normal kidney function, using data from the Health and Retirement Study (HRS) and the China Health and Retirement Longitudinal Study (CHARLS). Methods We used CKD-EPI to estimate glomerular filtration r...

Fan Zhang, Yue Xing, Yan Bai et al. · 0 citations
Review Open access Oct 2026

Non-pharmacological interventions and frailty-related outcomes in maintenance dialysis patients: a narrative review of evidence published since 2020

Frailty is common among adults receiving maintenance hemodialysis (HD) or peritoneal dialysis (PD) and is associated with mortality, hospitalization, impaired physical function, and reduced quality of life. In a multimorbid population vulnerable to polypharmacy and treatment burden, non-pharmacological approaches may b...

Fan Zhang, Kai-Li Lu, Wanhaier Abudoureheman et al. · 0 citations

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