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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ya-Xin Liu

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Review Open access Sep 2026

Skin physiologically based pharmacokinetic modeling: current research progress, software comparison, and future perspectives

Abstract Transdermal and topical delivery systems (TDS) have emerged as the third-largest route of administration due to their ability to bypass first-pass metabolism and maintain stable plasma concentrations. Skin physiologically based pharmacokinetic (PBPK) models mechanistically characterize the percutaneous absorpt...

Ya-Fen Li, Yu-Xiao Li, Ya-Xin Liu et al. · 0 citations

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