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Ya-Wen Pan

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Open access Sep 2026

Predicting early recurrence of craniopharyngioma using multi-omics radiomic modeling: a retrospective cohort study

Craniopharyngiomas (CPs) are benign tumors arising in the sellar and suprasellar regions, but they frequently recur after surgery because of their proximity to critical neurovascular and hypothalamic structures. This study aimed to develop and validate a habitat-based multimodal radiomics model for early postoperative...

Kun Hou, Ya-Dong Wang, Teng-Yun Guo et al. · 0 citations
Review Open access Sep 2026

Heterogeneity in cancer: molecular mechanisms and therapeutic strategies

The Holistic Integrative Tumor Ecosystem Theory (HITET) is proposed, a five-dimensional framework connecting these scales through functional interfaces that synthesizes how genetic alterations, cellular plasticity, metabolic programs, immune and stromal interactions, spatial gradients, organ-specific environments, micr...

Yong-Lin He, Liang Niu, Yan-Ming Ren et al. · 0 citations

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