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Ya-Qin Zhang

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#artificial intelligence Preprint Sep 2026

PFArena: Benchmarking Language Models for Protein Modification

The evaluation reveals that model performance shifts systematically with the availability of target-specific experimental evidence: PLMs demonstrate proficiency in open-ended single-mutant generation by leveraging protein-specific priors, whereas LLMs and agents perform strongly in multi-mutant ranking, particularly wh...

Ya-Wen Ouyang, Xin-Bo Zhang, Zi-Yuan Ma et al. · 0 citations
Jul 2026

Weak-to-Strong Generalization via Direct On-Policy Distillation

Direct On-Policy Distillation (Direct-OPD) is proposed, which transfers the teacher's RL-induced policy shift instead of running sparse-reward RL on the target model and consistently leverages weaker teachers to improve stronger target models.

Shiyuan Feng, Huan Gao, Haohan Chi et al. · 8 citations · ⚡1
Preprint Jul 2026

Spectral Rewiring for Exploration, Purification, and Model Merging

Subspace-Aligned Rewiring (SAR) shows that extracting reasoning-effective updates from parameter geometry can serve as a training-free mechanism to improve reasoning and multi-domain performance.

Zhilong Zhang, Hongli Yu, Huan Gao et al. · 0 citations
#artificial intelligence Preprint Aug 2026

Open-MOPD: Diagnosing and Fixing Capability Imbalance in Multi-Teacher On-Policy Distillation

Open-MOPD, a principled framework incorporating token-share balancing, gap-aware dynamic budget allocation, and student reward refresh, systematically restore cross-domain balance, elevating headroom recovery from 35.6% to 83.4% in a single deployable student.

Huan Gao, Haohan Chi, Yong Yan et al. · 12 citations · ⚡6

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