Author

Ya-Ping Zhang

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Open access Aug 2026

GWAS and multi-omics uncover the SLC6A3 locus for canine stranger-directed social anxiety and implicate NRIP3 in dopaminergic network regulation

The social anxiety disorder (SAD) is one of the most common mental health disorders, often developing in adolescence. It can severely impair educational achievement, career progression, and social functioning. Certain individuals within the Chinese Kunming dog (CKD) population display spontaneous, SAD-like behaviors to...

Huairen Zhao, Ju-Dong Li, Jing Li et al. · bioRxiv · 0 citations

Open access Sep 2026

Systematic benchmarking and optimal strategy selection of cross-species integration methods

Abstract Single-cell RNA sequencing provides an unprecedented resolution for cellular heterogeneity and gene regulation, fostering cross-species comparative analyses with increasing interspecies data. However, integrating single-cell transcriptomic data faces challenges, including gene selection, evolutionary distance,...

Ruo-Lin Wang, Jun-Juan Zheng, C. Mao et al. · Briefings in Bioinformatics · 0 citations

Open access Jul 2026

A rugged life: how host-microbiome adaptations associated with the semi-feral lifestyle of gayal (Bos frontalis).

Multi-omics findings suggest a host-microbiome system potentially associated with the utilization of chemically complex, low-quality forage, providing a framework for understanding digestive features of browsing ruminants and for conserving host-associated gastrointestinal microbiomes.

Yuming Chen, Juntao Ma, Zhifan Guo et al. · npj Biofilms and Microbiomes · 1 citation