Single-cell transcriptomics links HPV transcript abundance to malignant epithelial heterogeneity and redistribution of cell-cell communication across cervical lesions
Persistent high-risk Human Papillomavirus (HPV) infection is a prerequisite for most cervical cancers, but only a subset of infections progress to invasive disease. This study investigated associations between HPV transcript abundance, malignant epithelial heterogeneity, inferred cell-state trajectories, and microenvir...