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Open access Oct 2026

ATF4 Activation Promotes All-trans-Retinal-Driven Retinopathies in Mice

Impaired clearance of all-trans-retinal (atRAL) during the visual cycle leads to retinal degeneration, which is closely associated with autosomal recessive Stargardt disease (STGD1) and dry age-related macular degeneration (dry AMD). Transient activation of activating transcription factor 4 (ATF4) generally supports ce...

Kun-Han Yang, Chao-Feng Yu, Dan-Xue He et al. · 0 citations
Open access Jan 2026

Changing Epidemiology of Refractive Disorders in the Western Pacific Region, 1990–2023: Evidence From the Global Burden of Disease Study 2023

Introduction Refractive disorders (RDs) are a major cause of vision impairment worldwide. Although age‐standardised rates have generally declined, the absolute burden, demographic drivers and future trends of RDs in the Western Pacific Region (WPR) remain incompletely characterised. This study assessed the long‐term ep...

Yu-Qi Jiang, Shi-Nan Wu, Yu-Ling Chen et al. · 0 citations

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