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Author

Ya-Juan Su

1 paper indexed here

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Sep 2026

POLE2 of tumor cells promotes OPN secretion based on PCLAF to drive M2 macrophage polarization in clear cell renal cell carcinoma.

A comprehensive NFATc2/POLE2/PCLAF signaling axis that promotes ccRCC progression via OPN-mediated M2 macrophage polarization, providing a solid rationale and potential therapeutic targets for developing novel immunocombination therapies is unveiled.

An-Rui Li, Jing-Wen Xu, Zhi-Hang Wu et al. · 0 citations

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