Open access
Sep 2026
IGF‐1/SLC25A33 Maintains Blood‐Labyrinth Barrier Integrity by Suppressing TGF‐β/Smad2‐Mediated Pericyte Activation in Age‐Related Hearing Loss
ABSTRACT Age‐related hearing loss (ARHL) is a prevalent sensory disorder in the elderly, yet the molecular mechanisms underlying cochlear aging remain incompletely understood. While insulin‐like growth factor 1 (IGF‐1) has been implicated in ARHL, its role in the stria vascularis, particularly in pericyte‐mediated bloo...
Rui Xu, Jia Tang, Huan Lin et al.
· Aging Cell · 0 citations