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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ya-Jie Wang

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Open access Oct 2026

Receptor-induced activation of MERS-CoV spike revealed by time-course cryo-EM

The Middle East respiratory syndrome coronavirus (MERS-CoV) initiates infection by engaging its host receptor dipeptidyl peptidase 4 (DPP4), which activates the viral spike (S) glycoprotein. However, how receptor binding is structurally coupled to membrane fusion has remained unclear. Here, using cryo–electron microsco...

Ya-Jie Wang, Xi-Yuan Pan, Yuxuan Jiang et al. · 0 citations

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