Circ_0004801 promotes tau hyperphosphorylation and cognitive impairment in Alzheimer's disease through the miR-7688-5p/TTBK1 axis.
Circ_0004801 acts as an upstream regulator of TTBK1 by sequestering miR-7688-5p, thereby promoting tau hyperphosphorylation and cognitive impairment in AD and may represent a potential target for tau-directed intervention.