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MicroRNAs in Colorectal Cancer Immunotherapy: Biomarkers, Resistance Mechanisms, and Strategies to Convert “Cold” Tumors to “Hot”
Colorectal cancer (CRC) remains a major cause of cancer morbidity and mortality. Immune checkpoint inhibitors (ICIs) have transformed the treatment of microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) CRC, yet most CRCs are microsatellite-stable/mismatch repair-proficient (MSS/pMMR) and remain poor...