Author

Y. Zeighami

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Open access Sep 2026

Vascular and neurodegenerative contributions to cognitive decline and multidomain progression in de novo Parkinsons disease

INTRODUCTION: Cognitive decline in Parkinsons disease (PD) may reflect interacting neurodegenerative and cerebrovascular processes, but their distinct temporal contributions remain unclear. METHODS: Newly diagnosed, untreated PD participants from the PPMI who were cognitively normal at baseline and had at least three y...

R. Moqadam, H. Azizi, S. Raeesi et al. · medRxiv · 0 citations

Open access Sep 2026

Sex Differences in the Associations between Education, Neuropathology, and Cognition

IMPORTANCE Autopsy evidence on sex-specific associations of education with neuropathology and cognition is limited. OBJECTIVE To test sex differences in education associations with neuropathologic burden and cognition. DESIGN Cohort study of data collected from September 2005 through August 2024. SETTING Multicenter au...

S. Raeesi, Y. Zeighami, C. Morrison et al. · medRxiv · 0 citations