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Open access Sep 2026

Synergistic targeting of EP300/CBP and EYA co-activators collapses the rhabdomyosarcoma core regulatory circuit

A novel approach to target RMS transcription comprising simultaneous targeting of two distinctly acting transcriptional co-activators dually targets CRC-associated co-activators to cooperatively suppress the RMS transcriptome and enforce cell death.

Alrik Gustafson, S. Nance, B. Gryder et al. · 0 citations

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