Review
Open access
Aug 2026
Mitochondrial resilience: a convergent framework for pathogenesis and neuroprotection in Parkinson’s disease
This integrated framework reframes PD as a disorder of impaired cellular maintenance rather than solely a consequence of late-stage degenerative processes, and provides a translational shift from mechanism-based biomarkers to early detection of mitochondrial failure and supports therapeutic strategies aimed at restoring mitochondrial function and resilience.
Oscar Arias-Carrión, Magdalena Guerra-Crespo, L. O. Soto-Rojas et al.
· Frontiers in Pharmacology · 0 citations