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Author

Y. Shirakami

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Open access Sep 2026

Limited impact of NLRP3 inflammasome deficiency on diet-induced metabolic dysfunction-associated steatohepatitis in mice

Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD) and a growing cause of chronic liver disease worldwide. Although the NLRP3 inflammasome has been implicated in MASH pathogenesis, its contribution remains controversial acros...

Daisuke Taguchi, Y. Shirakami, Toshihide Maeda et al. · 0 citations
Open access Aug 2026

A 12-week home-based exercise program with nutritional guidance is associated with improved functional capacity in chronic liver disease.

BACKGROUND & AIMS Although exercise therapy improves physical function in chronic liver disease (CLD), structured programs remain underutilized in routine hepatology care. We evaluated the feasibility, safety, and potential functional impact of a structured home-based exercise program in patients with CLD. METHODS In...

S. Unome, Takao Miwa, Yoshihiko Atago et al. · 0 citations

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