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Open access Oct 2026

FMRI-guided focal transcranial magnetic stimulation of anterior cingulate cortex reduces opioid seeking and restores connectivity.

Relapse remains a major challenge in opioid addiction treatment. Transcranial magnetic stimulation (TMS) has emerged as a potential therapeutic strategy for addiction, yet results had been mixed due to empirically selected stimulation targets and limited knowledge of neural circuit engagement. Here, we used a focal rat...

Zi-Lu Ma, Ying Duan, Hieu Nguyen et al. · 0 citations
Open access Oct 2026

The Nucleus Accumbens Dorsomedial Column: Distinct Anterior–Posterior Inputs and Activation Inversely Associated With Opioid Relapse

Anatomical studies suggest that a dorsomedial region of the nucleus accumbens (dmACB) forms a basal ganglia‐like closed‐loop circuit with medial ventral pallidum (mVP), lateral hypothalamic area (LHA), and paraventricular thalamic nucleus (PVT). The circuit's topographic organization is unknown. We first used anterogra...

Kenichiro Negishi, Vanessa I. Navarro, Mona S. Pishgar et al. · 0 citations

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