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Open access Sep 2026

Synthetic adjuvants to potentiate the immune response against rAg85B by nasal route

Respiratory infections remain a relevant global health concern nowadays. The rapid dissemination and high mutational ratio of some pathogens, amid human demographic drivers, increases their pandemic potential. On the other hand, some bacterial infections have re-emerged with new resistant variants, supporting the need...

Rong Chen, Chang-Zan Tan, Wen Li et al. · 0 citations
#protein folding Open access Aug 2026

Regulation of Extracellular HMGB-1 Alarmin Levels by CIGB-300 Anticancer Peptide In Vitro and In Vivo

Data reveal for the first time that CIGB-300 treatment is able to induce extracellular HMGB-1 release in vitro and in vivo which could be indicative of ICD induction in some kinds of tumors; furthermore, the induction of extracellular HMGB-1 alarmin as a putative CIGB-300 response biomarker merits further investigation...

Daylen Aguilar-Noriega, Ying Yi, Jamilet Miranda et al. · 0 citations

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