Open access
Aug 2026
ABRL8301, a Novel 2-Methoxyestradiol Derivative, Mitigates Progressive Pulmonary Fibrosis by Downregulating 11β-Hydroxysteroid Dehydrogenase 1.
Progressive pulmonary fibrosis (PPF) is a severe lung disease characterized by persistent tissue damage and scarring, with no curative therapies currently available. The multifactorial and poorly understood pathogenesis complicates drug development, highlighting the need for novel multi-targeted anti-fibrotic therapeut...
So-Won Heo, Junghwan Choi, Yeonhwa Song et al.
· European Journal of Pharmaco... · 0 citations