Author

Yang Lou

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Open access Sep 2026

NEAT1 Coordinates a PDLIM5–CACNA1C Regulatory Program Associated with a Potentially Arrhythmogenic Cardiomyocyte State in the Border Zone During Early Myocardial Infarction

Patients with early-stage myocardial infarction (MI) are at high risk of malignant ventricular arrhythmias, yet the cell-type-specific molecular landscape associated with post-infarction arrhythmogenesis has not been systematically characterized. This study integrates single-nucleus and spatial transcriptomics to defin...

Jiu-Xiao Zhao, Qian Zhu, Y. Lou et al. · International Journal of Mol... · 0 citations

Case report Open access Jan 2026

A Novel Mutation of the FBN1 Gene in a Chinese Family With Marfan Syndrome and Unanticipated Discoveries of Family Members

This study expands the mutational spectrum of FBN1, establishes functional evidence for the pathogenicity of the LDLR variant, and represents the first report of a pediatric individual carrying three coexisting pathogenic variants for rare diseases.

Hang Shi, Xue-Jian Han, Shu-Kai Xing et al. · Genetics Research · 0 citations