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Sep 2026

Decoding cell division history and lineage-resolved phenotypic patterns from single-cell barcode and transcriptomic data.

The cell division tree encodes how proliferation and differentiation generate cellular diversity during multicellular development. Advances in single-cell RNA sequencing and CRISPR-based lineage tracing have enabled retrospective reconstruction of these histories at single-cell resolution. Here, we present FateScape, a...

Xiao-Chen Yu, Zi-Hao Wang, Zhen-Quan Zhang et al. · 0 citations

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