137. Succinate induces compulsive-like behavior via medial prefrontal cortex glutamatergic neuron excitation-inhibition imbalance in male mice
Abstract Background Obsessive-compulsive disorder (OCD), a disabling psychiatric disorder characterized by obsessions (commonly anxiety-associated) or compulsions, remains mechanistically elusive, which hinders therapeutic development. Our previous study revealed elevated succinic acid levels in both the serum of OCD p...