Xun-Yao Wu

Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock‐Associated Immunosuppression: A Single‐Cell Multi‐Omics Study

Sepsis‐induced immunosuppression contributes to poor outcomes in sepsis patients, yet the mechanisms underlying T cell dysfunction remain incompletely understood. We integrated single‐cell RNA sequencing (scRNA‐seq), paired single‐cell T cell receptor sequencing (scTCR‐seq), bulk RNA sequencing (RNA‐seq), and flow cyto...