Review
Open access
Jul 2026
Extracellular vesicle-mediated immune crosstalk in rheumatoid arthritis synovium: mechanistic insights and translational challenges
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease marked by persistent synovial inflammation, autoantibody production, cartilage damage, and bone erosion. Biologic disease-modifying antirheumatic drugs (DMARDs) and targeted small-molecule therapies have improved disease control, but durable remission r...
Feng Luo, Xuemei Yuan, Heng Zhou et al.
· Frontiers in Immunology · 0 citations