Retrieval-Augmented Generation (RAG) relies critically on the effectiveness of its retrieval component. Dense retrieval with Approximate Nearest Neighbor (ANN) search is efficient but relies on symmetric similarity metrics that can limit the modeling of directional relevance. Generative retrieval addresses this limitat...
Yifei Zhang, Hao Zhu, Haoran Shi et al.· Proceedings of the 32nd ACM...· 0 citations
The continuous accumulation of genetic mutations in influenza A viruses (IAVs) drives antigenic drift, necessitating precise antigenic prediction for optimal vaccine strain selection. While sequence-based methods have advanced antigenic surveillance, they neglect the three-dimensional structural context that fundamenta...
This work proposes eXtreme Gradient Boosting LoRA (XGBLoRA), a novel framework grounded in gradient boosting theory that provides theoretical analysis establishing convergence guarantees and expressiveness bounds, which formally justify why weaker (lower-rank) adapters, when properly combined, can match or exceed the p...
Yifei Zhang, Hao Zhu, Haoran Shi et al.· Proceedings of the 32nd ACM...· 0 citations
Abstract Motivation Advances in spatial transcriptomics (ST) technologies have made it possible to jointly acquire gene expression and histological image information while preserving spatial coordinates. This breakthrough presents unprecedented opportunities for the precise dissection of spatial heterogeneity in comple...
SpatialGEO, a geometric-aware deep learning framework that integrates gene expression profiles with spatial coordinates to generate biologically meaningful low-dimensional embeddings, enabling the dissection of complex tissue architectures, achieves superior performance in tissue structure dissection and data denoising...
Fine-tuning Large Language Models (LLMs) has become a crucial technique for adapting pre-trained models to downstream tasks. However, the enormous size of LLMs poses significant challenges in terms of computational complexity and resource requirements. Low-Rank Adaptation (LoRA) has emerged as a promising solution, yet...
Yifei Zhang, Hao Zhu, Haoran Shi et al.· Proceedings of the 32nd ACM...· 0 citations
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