Xue-Qiong Zhang

Fluorinated 4-Methylideneisoxazolidin-5-ones: Synthesis and Apoptosis-Inducing Antiproliferative Activity

Sesquiterpene lactones, featuring an α-methylene-γ-lactone moiety, serve as lead compounds for anticancer drug development. Their nitrogen-containing analogues, namely, 4-methylideneisoxazolidin-5-ones, have attracted special attention for their promising anticancer properties. Installing a fluorine atom at the exocy...