BACKGROUND
Rare loss-of-function (LoF) variants in Intersectin-1 (ITSN1) have recently been identified as strong genetic risk factors for Parkinson's disease (PD) in individuals of European ancestry.
OBJECTIVE
The aim was to determine whether this association extends to other populations.
METHODS
We analyzed whole-...
Chun-Yu Li, R. Ou, Q. Wei et al.· Movement Disorders· 0 citations
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis typically presents with psychiatric symptoms, seizures, and cognitive dysfunction. Movement disorders, when present, usually coexist with these features. We report a rare case of anti-NMDAR encephalitis in a 30-year-old female who presented with isolated left...
Youjia Liu, Si-Hui Chen, Yan-Yun Wu et al.· Frontiers in Immunology· 0 citations
Amyotrophic lateral sclerosis (ALS), the most common type of motor neuron disease, primarily manifests as progressive weakness, atrophy, fasciculations, bulbar palsy, and pyramidal tract symptoms. Accumulating evidence indicates that the pathological spectrum of ALS extends beyond the pyramidal and neuromuscular motor...
Xin-Yao Gao, Ting-Ting Wang, Si-Hui Chen et al.· Frontiers in Genetics· 0 citations
