Cell–Cell Communication in Embryonic Kidney Development: Insights from Single-Cell and Spatial Transcriptomics
Embryonic kidney morphogenesis depends on the coordinated communication among ureteric epithelium, nephron progenitors, stroma, endothelium and differentiating nephrons. Classical studies established central roles for glial cell line-derived neurotrophic factor (GDNF) signaling through the RET proto-oncogene receptor t...