Achieving general asymmetric catalytic manifolds that accommodate broad substrate diversity remains a long-standing and highly sought-after goal in synthetic chemistry. Herein, we report an efficient cobalt-catalyzed desymmetric hydrogenation of structurally diverse cyclic 1,2- and 1,3-diacid anhydrides, enabling acces...
Lei Yang, Deng-Hong Yan, Yuan-Zheng Wang et al.· Angewandte Chemie· 0 citations
Enantiopure aryloxypropionic acid herbicides are of considerable importance in modern crop protection, creating a strong demand for efficient catalytic approaches to their synthesis. Herein, we report a Rh/(S,R)-DTB-YanPhos-catalyzed asymmetric hydroformylation of readily available aryl vinyl ethers, affording chiral 2...
Jian-Qiang Zheng, Lin-Na Qi, Cai You et al.· Chemistry· 0 citations
Influenza A remains a major seasonal public health burden. With the approval of onradivir, PB2 has emerged as an attractive antiviral target due to its unique and conserved structural features. Herein, using onradivir as the lead, we employed bioisosteric replacement strategies to design a series of derivatives for SAR...
Yujian Yang, Bin-Hao Rong, Xing-Yu Zhou et al.· Journal of Medicinal Chemist...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.