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Xu-Chao Gu

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Open access Sep 2026

Circulating ANGPTL4 predicts CKD and ESKD risk: insights from large-scale proteomics and senescence mechanisms

The global burden of chronic kidney disease (CKD) is increasing significantly, with aging recognized as a major risk factor associated with accelerated biological aging and poor renal outcomes. Growing evidence links angiopoietin-like protein 4 (ANGPTL4) to both aging and CKD pathogenesis, suggesting its potentia...

Hung-Chen Chang, Rui-Jin Lin, Xu-Chao Gu et al. · 0 citations

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