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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiu-Ting Liu

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Review Open access 2026

Unveiling and harnessing: the tumor microenvironment in RAS/MAPK pathway-targeted therapy

Rational combination strategies are outlined that simultaneously target the RAS/MAPK axis and key TME vulnerabilities, such as immunotherapy combinations, CAF reprogramming, and ECM normalization, to overcome stromal-mediated resistance and achieve deeper, more sustained clinical responses.

Wen-Hao Ma, Xing-Yu Guo, Xiu-Ting Liu · 0 citations

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