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This review summarizes the classification and bioactive properties of triterpenoids, together with the challenges and potential solutions associated with their microbial synthesis, and proposes metabolic engineering and synthetic biology strategies for optimizing matter and energy transmission and thereby enhancing tri...
As a high-value-added amino acid derivative, trans-4-hydroxy-L-proline (T-4-Hyp) faces key bottlenecks in its microbial production from glucose, including insufficient precursor supply and an imbalance between cell growth and product biosynthesis. In this study, we successfully constructed an engineered Escherichia col...
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