Author

Xin-Yu Jiao

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Open access Aug 2026

Establishment of a cryopreservation system and evaluation of post-thaw effects for Piao chicken primordial germ cells

Primordial germ cell (PGC) cryobanking provides an alternative strategy for conserving endangered chicken genetic resources; however, evidence regarding the post-thaw stability of breed-specific PGCs remains limited. This study evaluated a stepwise two-solution cryopreservation procedure based on CO₂-independent medium...

Yi-Fan Xi, Fu-Fu Cheng, Qing-Qing Geng et al. · Journal of Genetic Engineeri... · 0 citations

Open access Jul 2026

Integrated metabolomic and transcriptomic analyses reveal that glutamine promotes chicken primordial germ cell-like cell specification potentially through α-ketoglutarate

Glutamine promotes the specification of chicken PGCLC and correlates with alterations in cellular metabolism and increased H3K4me2 levels during differentiation, providing new insights into the metabolic basis of PGC formation and a foundation for improving PGC culture and expansion in poultry.

Qing-Qing Geng, Lei Zhang, Zhe Wang et al. · Animal bioscience · 0 citations

Review Open access Jul 2026

Clustered regularly interspaced short palindromic repeats‑associated protein 9 (CRISPR-Cas9) based genome editing in avian primordial germ cells: Comparative technologies, translational applications, and regulatory challenges

This review critically evaluates genome-editing tools in avian PGCs, including CRISPR/Cas9, transcription activator-like effector nucleases (TALENs), base editing, and prime editing, and their applications.

Mazhar Farooq, Dayong Han, Lei Zhang et al. · Poultry Science · 0 citations