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Xinyang Jiang

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Preprint Sep 2026

PAPT++: Risk-Aware Adversarial Tuning and Generation for Single Domain Generalization

Single domain generalization (SDG) aims to learn a model from one labeled source domain that generalizes to unseen target domains. A common strategy is to enrich the source distribution with augmented or generated samples, and recent text-to-image (T2I) diffusion models provide a strong generative prior for this purpose. However, diversity alone is insufficient for robust generalization, because useful generated samples should also capture variations that the current classifier finds difficult. Motivated by distributionally robust optimization (DRO), we define a semantic ambiguity set in the class-conditional generative space of a pretrained T2I model and search it for samples with high classification loss under the current classifier. To this end, we introduce PAPT++, a risk-aware adversarial generation-training framework for SDG. PAPT++ first learns diverse semantic reference images for each class through image-text alignment and intra-class diversity regularization. These references then serve as denoising targets during classifier-guided diffusion synthesis, reducing semantic drift while guiding generation toward challenging variations. The generated samples are combined with the source data to update the classifier, and the updated classifier guides the next synthesis round in return. In this way, PAPT++ progressively exposes the classifier to challenging yet semantically consistent variations. Extensive experiments on standard SDG benchmarks demonstrate the superiority of the proposed PAPT++ method and the effectiveness of its main components.

Zhipeng Xu, De Cheng, Xinyang Jiang et al. · 0 citations
Preprint Jul 2026

A report-grounded vision-language foundation model for colonoscopy from 280000 routine reports

Vision-language models remain underused in colonoscopy despite the rich expert descriptions recorded in routine reports. These reports document lesion appearance, size and location but summarise entire procedures rather than caption individual frames, leaving clinical findings only weakly linked to the corresponding images. Here we develop EndoCLIP, a colonoscopy vision-language foundation model trained on 125,756 lesion-level image-text pairs progressively recovered from 280,476 routine colonoscopy records. Across lesion-level image-text retrieval, structured report generation and six multi-centre clinical classification tasks, EndoCLIP outperforms general-purpose and biomedical vision-language encoders in both zero-shot and linear-probe settings. On benign-versus-malignant classification, its linear probe approaches the performance of expert readers in a blinded study involving 12 endoscopists. These results suggest that recovering finding-to-frame correspondence can transform routine documentation into scalable supervision, enabling clinical targets to be specified in language rather than separately annotated for each task.

Jia Yu, Yan Zhu, Yili He et al. · 0 citations

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