Review
Open access
Jul 2026
Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance
Colorectal cancer (CRC) is a highly lethal malignancy worldwide. Lactylation, which serves as a key metabolic‐epigenetic bridge driving malignant progression, is involved in CRC development, metastasis, immunosuppression, and drug resistance. This review systematically outlines the biological functions of lactate and t...
Shuilan Yao, Yunpeng Liang, Xinwen Liang et al.
· Journal of biochemical and m... · 1 citation