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Xingyu Liao

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Aug 2026

DeepCRISPR-Typer: Accurate CRISPR-Cas Identification and Subtyping in Metagenomes via Integrated Deep Learning

DeepCRISPR-Typer is presented, a comprehensive computational framework integrating a large protein language model (TEMC-Cas), a deep sequence feature extractor (CRISPR-RepTyper), and an adaptive targeted HMM profiling strategy that significantly reduces computational overhead by dynamically invoking subtype-specific HMM subsets.

Long Wen, Minghui Jing, Yanyan Li et al. · 0 citations

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