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Preprint Aug 2026

SurroPilot: An LLM-Assisted Platform for Heterogeneous Surrogate Endpoint Evaluation in Clinical Trials

Surrogate endpoints are widely used in clinical trials to accelerate treatment evaluation, yet their validity may vary substantially across patient subgroups. Although recent advances in heterogeneous causal mediation analysis enable subgroup-specific surrogate evaluation, applying these methods requires substantial ex...

Xingyu Li, Peng Wei · 0 citations

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