The Mechanism of the Parkin-CMA-NLRP3-PANoptosis Signaling Axis in Parkinson's Disease: From Molecular Basis to Therapeutic Strategies.
A systematic review systematically delineates the molecular framework of the Parkin‑CMA‑NLRP3‑PANoptosis signaling axis and summarizes translational progress of small‑molecule compounds and gene therapies targeting individual components within this cascade.