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Author

Xing-Zhe Li

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2 papers indexed here

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Open access Aug 2026

A cuproptosis-inducing covalent organic framework synergizes with oncolytic virus for tumor radiotherapy

Acquired radioresistance limits effective radiotherapy. Cuproptosis is a copper-dependent form of cell death driven by mitochondrial copper accumulation and lipoylated protein aggregation. Building on evidence that radioresistant cancer cells exhibit increased cuproptosis susceptibility, here we combine a radiation-res...

Yuantong Liu, Ke-Er Liu, Han-Qi Li et al. · 0 citations
Review Oct 2026

Versatile covalent organic frameworks for cancer immunotherapy.

Cancer immunotherapy has produced substantial clinical benefit, yet its efficacy remains limited in patients with immunologically "cold" tumors, which are characterized by poor T-cell infiltration and a suppressive tumor microenvironment (TME). Strategies for converting cold tumors into immunologically "hot" phenotypes...

Qi-Chao Yang, Li-Xuan Xu, Meng-Meng Cao et al. · 0 citations

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