Review
Open access
Sep 2026
HIV-driven tumor ecosystem: from chronic immune dysfunction to cancer evolution
This review comprehensively examines the components and dynamic changes within the tumor ecosystem of HIV-infected patients, focusing on how HIV-mediated CD4+ T-cell depletion, immune checkpoint dysregulation, chronic antigenic stimulation, and direct effects of viral proteins such as Tat and Nef facilitate tumor immun...
Guang Zhou, Juan-Yan Liao, Hao-Lin Tang et al.
· Frontiers in Microbiology · 0 citations