Open access
Sep 2026
Histone demethylase Kdm2a aggravates pressure overload-induced myocardial fibrosis through global and locus-specific H3K36me2 chromatin remodeling.
Subclinical hypertensive heart disease (SHHD) is a precursor to heart failure and ultimately progresses to impaired left ventricular systolic function, which is characterized by myocardial hypertrophy leading to compromised contractility and by myofibroblast proliferation and activation leading to decreased myocardial...
Lian-Pin Wu, Jia-Qi Chen, Yi-Zhe Wang et al.
· Clinical science · 0 citations