A major challenge in auricular reconstruction is the endochondral ossification of engineered cartilage after subcutaneous implantation. To overcome this, we developed a functionally tailored, hybrid hydrogel scaffold that integrates anti‐angiogenic therapy with biomimetic architecture to stabilize the chondrogenic ph...
Bo-Qing Zhang, Yu Liu, Hai-Rui Li et al.· Advanced Functional Material...· 0 citations
Infection is the most common complication of osteoporotic fractures, often characterized by bacterial resistance and intracellular infection, posing a major challenge in the treatment of osteoporotic fractures. Here, we developed a multifunctional biomimetic Trojan horse nanosystem based on hydroxyapatite nanotubes (NT...
Yong-Di Wang, Lu-Ping Liao, Yuxiang Zhang et al.· Advances in Materials· 0 citations
Osteoarthritis (OA), a prevalent chronic degenerative joint disorder, affects hundreds of millions of people worldwide and has become a leading cause of joint pain and functional impairment in middle-aged and elderly populations. It not only severely compromises patients’ quality of life but also imposes a significant...
Chenxin Liu, Wenling Dai, Xingchen Zhao et al.· Collagen and Leather· 0 citations
This work establishes a sustained-delivery strategy that couples matrix cues with microenvironment regulation for high-quality wound repair, and achieves key regenerative outcomes with enhanced hair follicle-associated regeneration and reduced scar-prone remodeling.
Ziang Wang, Bin Zhang, Pengchao Zhang et al.· Acta Biomaterialia· 0 citations
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