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Author

Xin-Zhuo Zhang

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Open access Sep 2026

Trichinella spiralis galectin disrupts gut epithelial integrity and mediates larval invasion via acting MUC13- ROCK2/MAPK pathway

Background Gut epithelium serves as a critical barrier against Trichinella spiralis larval invasion, parasite-derived galectins are involved in host–parasite interactions, including invasion and immune modulation. This study investigated the role of T. spiralis galectin (Tsgal) in gut epithelial barrier disruption and...

Ru Zhang, Yao Zhang, Xin-Zhuo Zhang et al. · 0 citations
Open access Sep 2026

Molecular characterization of a novel Trichinella spiralis aspartyl protease and its role in the larval invasion of host intestinal epithelial cells

The aim of the present study was to characterize the molecular properties of a novel Trichinella spiralis aspartic protease (TsEasp) and to investigate its role in the larval invasion of host intestinal epithelial cells. The full-length TsEasp cDNA was cloned and expressed, and recombinant TsEasp protein (rTsEasp) was...

Yao Zhang, Ru Zhang, Xin-Zhuo Zhang et al. · 0 citations

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