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Review Open access Sep 2026

A cardiometabolic risk phenotype index integrating insulin resistance, systemic inflammation, and psychological burden for mortality risk stratification in metabolic dysfunction-associated steatotic liver disease: an exploratory longitudinal analysis of a nationally representative cohort

Metabolic dysfunction-associated steatotic liver disease (MASLD) is being increasingly recognized as a systemic cardiometabolic disorder rather than a liver-limited condition. However, the combined association of insulin resistance, systemic inflammation, and depressive symptoms with mortality remains unclear. Therefor...

Yan Chen, Kai-Ling Xie, Ning-Kun Xiao et al. · 0 citations
Review Sep 2026

Association between the cholesterol-high-density lipoprotein-glucose index and the prevalence of depressive symptoms among U.S. adults: An exploratory analysis of nationally representative cross-sectional data.

In this nationally representative sample of U.S. adults, the CHG index was positively associated with the prevalence of depressive symptoms and it was suggested that HOMA-IR and ALB may statistically account for part of this association.

Yan Chen, Ning-Kun Xiao, Qing-Zhi Zhou et al. · 0 citations
Review Open access Aug 2026

Neutrophil-to-high-density lipoprotein cholesterol ratio and prevalent cardiometabolic multimorbidity in older adults: an exploratory cross-sectional analysis

The neutrophil-to-high-density lipoprotein cholesterol ratio (NHR), a composite surrogate marker derived from neutrophil count and HDL-C, has been reported to be associated with various metabolic and cardiovascular diseases. This study aimed to investigate the association between NHR and cardiometabolic multimorbidity...

Yan Chen, Hao-Nan Ju, Qing-Zhi Zhou et al. · 0 citations

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