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Review Open access Sep 2026

Exosome-mediated muscle-bone crosstalk: mechanisms and therapeutic potential

Muscle and bone maintain homeostasis through biomechanical and molecular crosstalk. Disruption of this interaction leads to osteosarcopenia, a condition marked by concurrent muscle and bone loss. Exosomes carry proteins and nucleic acids between tissues and are now recognized as key mediators of intercellular communica...

Dong Chen, Jing Liu, Xin Liang et al. · 0 citations
Review Sep 2026

Pharmacological Research Progress on the Regulation of Bone Metabolism and Anti-osteoporosis by Active Ingredients of Rehmannia Glutinosa.

Active ingredients from Rehmannia show clear preclinical potential in both promoting bone formation and inhibiting bone resorption, and are hypothesized to offer possibly offering better safety compared to conventional chemical drugs, although this claim lacks direct clinical comparative evidence.

Ting-Ting Huang, Xin Zhang, Lang-Qing Yu et al. · 0 citations

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