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Xin-Yue Zhang

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Oct 2026

Discovery of the mechanism of Huangqi Guizhi Wuwu Decoction in the treatment of Diabetic Peripheral Neuropathy with Qi Deficiency and Blood Stasis based on the dynamic metabolic trajectory analysis.

ETHNOPHARMACOLOGICAL RELEVANCE Huangqi Guizhi Wuwu Decoction (HGWD), a classic Traditional Chinese Medicine formula, has shown clinical efficacy in the treatment of diabetic peripheral neuropathy (DPN) with Qi deficiency and blood stasis syndrome. However, its pharmacodynamic material basis and underlying therapeutic m...

Jing Wen, Li Yan, Yu-Jie Xiang et al. · 0 citations
Oct 2026

C-terminus of HSC70-Interacting Protein-Mediated Transforming Growth Factor-β 1 Protein Degradation Underlies the Anti-fibrotic Effects of Verbascoside in Pulmonary Fibrosis.

BACKGROUND Pulmonary fibrosis (PF) is a progressive and fatal interstitial lung disease with limited therapeutic options. Transforming growth factor-β1 (TGF-β1) is a master driver of fibrogenesis, but strategies to effectively degrade this protein remain underexplored. Verbascoside, a natural phenylethanoid glycoside,...

Jiang-Zhou Han, Shan-Shan Lu, Yan-Ping Zhu et al. · 0 citations

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