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Author

Xin-Yue Ju

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Open access Aug 2026

HOXC9 promotes cell proliferation and suppresses mitochondria-dependent apoptosis through the AKT/mTOR pathway in esophageal squamous cell carcinoma.

Homeobox C9 (HOXC9) is aberrantly expressed in multiple malignancies; however, its functional role in esophageal squamous cell carcinoma (ESCC) remains elusive. This study investigated the expression, function, and underlying molecular mechanisms of HOXC9 in ESCC. HOXC9 was evaluated via immunohistochemistry in 118 ESC...

Xin-Ya Yu, Ya-Jun Wang, Xin-Yue Ju et al. · 0 citations
Review Open access Aug 2026

A Data-Driven Atlas of CAR-Based Immunotherapy in Lung Cancer: Insights from Multidatabase Integration.

Lung cancer remains a leading cause of cancer-related mortality worldwide, and the clinical translation of chimeric antigen receptor (CAR)-based immunotherapy into solid tumors continues to be constrained by antigen heterogeneity, an immunosuppressive microenvironment, and stromal barriers that impede immune cell traff...

Fangkai He, Xing-Yu Zhu, Xiao-Lei Wang et al. · 0 citations

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