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Xin-Yuan Zhang

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Open access Oct 2026

Associations of food processing and dietary risk factors with colorectal cancer incidence in the NIH-AARP Diet and Health Study: A cohort study

Background Ultra-processed foods (UPF) account for >50% of energy intake by US adults. UPF intake can include dietary components linked to lower colorectal cancer (CRC) risk, such as whole grain and dairy products, and others linked to higher CRC risk, such as processed meats, potentially explaining the heterogeneity o...

L. Abar, Caitlin P. O'Connell, H. G. Hong et al. · PLoS Medicine · 0 citations

Open access Aug 2026

The LRRK2 R1441G+M1646T haplotype is associated with slower motor symptom progression in Parkinson’s disease

R1441G+M1646T carriers exhibit substantially slower motor progression than sporadic PD while M1646T carriers do not, and the effects of other LRRK2 variants on disease trajectory remain incompletely characterized.

Jackson G. Schumacher, Xin-Yuan Zhang, Jian Wang et al. · medRxiv · 0 citations

Open access Jul 2026

Multiple 24-Hour Urinary Sodium and Potassium Excretions and Type 2 Diabetes Incidence.

OBJECTIVE High sodium and low potassium intake, well-established dietary risk factors for hypertension, may induce insulin resistance and increase the risk of type 2 diabetes. However, previous research based on self-reported intakes is inconclusive. We examined the association of sodium and potassium intake, assessed...

Siwei Zhu, Xin-Yuan Zhang, R. Hamaya et al. · Diabetes Care · 0 citations